‘Lessons in Chemistry’ Star Brie Larson Became a ‘Jack of All Trades’ to Play Elizabeth, Showrunner Says

Lee Eisenberg has one person to thank for introducing him to Bonnie Garmus’ best-selling 2022 book “Lessons in Chemistry.”

“My wife read the book first and she said, ‘This is a series and you need to read this immediately,’” he said. “I don’t remember what I was reading at the time, but when my wife says that, I drop whatever I’m doing and I start reading. It was not surprising that I trusted her opinion and that she was right. I loved the book so much.”

So he got to work: He learned that a TV series based on the novel about a brilliant female scientist in the 1950s was already set up at Apple, with Brie Larson attached to star and exec-produce.